For central nervous system (CNS) applications, attempts are being made to deliver AAV gene therapy directly ... to be established in preclinical mouse disease models,” pointed out Nonnenmacher ...
UAB researchers have reversed metabolic dysfunction-associated steatohepatitis (MASH) in mouse models. MASH is a severe liver ...
They also demonstrated that using AAV to deliver both NeuroD1 and Dlx2, another transcription factor, regenerated GABAergic neurons in a mouse model of Huntington’s disease, significantly ...