The data clearly demonstrate that a single-antibody framework can harness diverse CDR sequences previously not found in combination, including CDR loops with foreign canonical structures ...

In the landmark Amgen v. Sanofi case (previously covered here), the Supreme Court affirmed that patent claims drawn to a genus of ...

Paratope-PLUS™ involves mutating each residue of an antibody's CDRs (Complementarity Determining Regions) to all 19 other amino acids, identifying every variant that retains or enhances function.