More information: Funing Lin et al, Structure-Based Design and Development of Phosphine Oxides as a Novel Chemotype for ...

Many other bacterial pathogens express proteases on their surface, and some of these proteases are related to Pla. Whether these proteases also serve to promote invasive disease awaits investigation.

in turn activating their protease functions. By the end of this game of proteolytic telephone in the horseshoe crab, a cleaved protein forms a clot that helps trap bacteria. The pharmaceutical ...

Schmitz’s research lab studies protease enzymes in TB-causing bacteria. These enzymes play critical roles in bacterial physiology. Previous work by his lab found that these proteases interact with ...

Some bacteria have developed CRISPR gene scissors ... now been able to show that the so-called SAVED domain of the CalpL ...

The antitryptic and antichymotryptic activity of human milk might prevent the absorption of endogenous and bacterial proteases in infants and thereby contribute to the passive protection of ...

These bacterial biosynthetic enzymes may potentially ... Interestingly, while the hydroxylase domain was initially predicted to be a protease based on its structural similarity to metalloproteases ...