In many cell types, proteins are asymmetrically distributed over the cell surface, which creates separate apical and basolateral membrane domains that uniquely contribute to cell and tissue function.
This photo shows the basolateral amygdala in a mouse. Fluorescent markers highlight the neurons that encode negative stimuli (in purple) and the neurons that preferentially encode positive stimuli ...
To their surprise, the localization of basolateral proteins was indistinguishable ... and were globally diminished along the brush border membrane by 3 wk after birth. Moreover, when functional ...
Thus, expression of an essential "house-keeping" gene such as Na + /K +-ATPase at the basolateral plasma membrane is maintained, whereas there is a downregulation in the expression of absorptive ...
Upon binding of desmopressin to V2 receptors in the basolateral membrane of the cells of the distal tubule and collecting ducts of the nephron, adenylyl cyclase is stimulated. The resulting ...