Renier Brentjens, a CAR T-cell pioneer, views armored CAR T-cells as a promising avenue for treating solid tumors and ...

The researchers examined CAR T cell-mediated cancer cell killing in a two-tumor mouse model. Their goal was to test whether synthetic cells could protect CD19+ tumors from CAR T cells, while leaving ...

Engineered cell therapies, such as CD19-targeted chimeric antigen receptor ... She will now test these “OX40L-CAR-Tregs" in human cells and mouse models, potentially paving the way for rapid ...