First-line medication for TB is a quadruple therapy regimen of rifampicin, isoniazid, pyrazinamide and ethambutol for two months, followed by a four month continuation phase of rifampicin and ...

The level of CYP3A4 expression may determine which patients best respond to certain drugs, and which patients experience side effects or even toxicity when the same dosage is administered.

Antagonized by strong inducers of CYP3A4 (eg, nevirapine, rifampicin), anesthetics (eg, halothane, methoxyflurane). Antagonizes glyceryl trinitrate, other antianginal drugs. Hypertension ...

The area under the curve of TMC207 halved when used with rifampicin, but early bactericidal activity is probably preserved. Mouse model studies suggest a synergistic relationship between TMC207 ...

Norgestimate 0.18mg, ethinyl estradiol 35mcg (7 tabs); norgestimate 0.215mg, ethinyl estradiol 35mcg (7 tabs); norgestimate 0.25mg, ethinyl estradiol 35mcg (7 tabs); inert (7 tabs). High risk of ...

Vilja Palkama, Studies on drug interactions between CYP3A4 inhibitors and anaesthetic drugs. Kirsti Villikka, Studies on drug interactions caused by rifampicin and dexamethasone in humans. Mirja ...

The National Institutes of Health has identified several CYP3A4 inducers, including "barbiturates (phenobarbital), ...