The compounds target NLRP3 systemically in the periphery or directly in the brain. The company’s lead compound is NT-0796, a small molecule with differentiated chemistry that is currently in a ...
Insilico Medicine (“Insilico”), a clinical-stage generative artificial intelligence (AI)-driven drug discovery company, today ...
et al. (2024). Exploring the efficacious subfractions and underlying mechanisms of Herba Siegesbeckiae against myocardial ischemia/reperfusion injury via the UCHL5/NLRP3 pathway. Acta Materia Medica.