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Chimeric RNAs and the proteins translated from them often have a causal role in tumorigenesis. They are also occasionally found at low levels in healthy cells. These phenomena were previously ...
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Self-amplifying mRNA vaccines appear safe in lab and animal testsmRNA vaccines contain instruction codes for ... indeed recombine with viruses under laboratory conditions, resulting in chimeric viruses (mixtures). To achieve this, you have to try very often ...
One concern is that insertional mutagenesis of the lentiviral DNA payload in in vivo CAR-Ts may cause secondary cancers.
“Autologous chimeric antigen receptor (CAR ... universal ‘off-the-shelf’ CAR-T cell therapies. “We can use our mRNA to encode a gene-editing protein to engineer T cells from a healthy ...
Federal support for mRNA vaccine research appears in jeopardy after KFF Health News reported Sunday that officials at the National Institutes of Health have directed scientists to remove all ...
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