DNA mismatch repair is a process that removes and replaces nucleotides that are erroneously inserted during DNA replication. Non-complementary bases on the newly synthesized DNA strand are ...

For patients with advanced or recurrent endometrial cancer, first-line Lenvima plus Keytruda didn’t significantly improve ...

The US Food and Drug Administration (FDA) has granted Breakthrough Therapy designation to a cancer drug called dostarlimab ...

specifically a modification called O 6-methyl guanine (O 6-meG), which is a modified DNA base guanine with a methyl group added to the oxygen in position 6. Normally, a cell's mismatch repair (MMR ...

During his undergraduate studies, he worked in the lab of Dr. Jennifer Surtees, where he investigated the contribution of DNA mismatch repair factors to trinucleotide repeat expansions. Maxwell joined ...

Microsatellite instability-high: a condition in which cancer cells have a high number of mutations in microsatellites, which are short, repeated DNA sequences. Mismatch Repair Deficienta: a condition ...

Princeton: Bristol Myers Squibb has announced that the European Commission (EC) has approved Opdivo (nivolumab) plus Yervoy ...