The classic digoxin effect ― or the “reverse checkmark” or “reverse tick” sign on the ECG ― is not considered an indication of toxicity. This is depicted below, followed by full 12 ...
Digoxin, originally derived from the foxglove flower, blocks the sodium/potassium ATPase pump. The mechanism by which this decreases atrioventricular (AV) conduction is not clear, butperhaps it is ...