“That indicated there must be some kind of coupling,” Morin said. Shimomura continued to study GFP and identified its chromophore in 1979. 4 Ultimately, though, he returned to studying bioluminescence ...

The ability of this protein to form a fluorescent chromophore in the absence of any additional factors has spurred wide applications of GFP as a genetically encoded marker and biosensor.

Figure 1: Fluoresence and phase-contrast microscopic evaluation of murine hematopoietic colonies for GFP expression. Figure 3: GFP expression in peripheral blood leukocytes from a rhesus macaque ...