Modern HIV medicine is based on a common genetic mutation. Now, researchers have traced where and when the mutation arose -- and how it protected our ancestors from ancient diseases.

Scientists extracted a near-complete HIV-1 genome from a lymph node that had been preserved in wax for more than 50 years. The sample stands as the oldest HIV-1 genome yet recovered, predating the ...

Paul Sharp and colleagues from the University of Nottingham Queens Medical Centre in England compared full-length genome sequences of chimpanzee HIV strains with inferred ancestral sequences for three ...

Today, thanks to antiretroviral drugs, HIV can be kept in check even if there is still no cure. However, a small biotech ...

Schematic representation of HIV-1 genome organization. The three coding reading frames are depicted along with their open reading frames (rectangles). Genome position is numbered according to HXB2 ...

Now, thanks to Tomas Cihlar’s and Wesley Sundquist’s contributions, the world is a step closer to preventing infections ...

HIV-1 particles are released from infected cells ... scientists have explored the structural changes of the virus capsid ...

The only remaining autonomous 'jumping gene' can only attach to, and stitch a copy of itself into, DNA when it builds up into large clusters and only as cells divide.

Undetectable drug-resistant forms of HIV have been identified by Yale School of Medicine researcher Michael Kozal, M.D., using an innovative genome sequencing technology that quickly detects rare ...

Viruses are known to use the genetic machinery of the human cells they invade to make copies of themselves. As part of the process, viruses leave behind remnants throughout the genetic material ...

Sundquist laid the groundwork in studying one of HIV’s proteins, the capsid, which creates a protective shell around the virus’ genome; Cihlar visited his labs and was impressed enough to take ...