In any case, these signals evoke a normal inflammatory response. Oxygen stress leads to keratinocyte damage. Ingestion of P. acnes by polymorphonuclear leukocytes may cause the release of ...

Next, Monteleone et al. investigated whether IL-21 can induce keratinocyte proliferation and epidermal hyperplasia as seen in psoriasis. Keratinocytes from healthy volunteers were shown to ...