Mutations that affect protein stability follow simple math rules, study shows
and the Wellcome Sanger Institute have discovered that mutations affect protein stability following remarkably simple rules.
Nature4y
Mutation detection and single-molecule counting using isothermal rolling-circle amplification
enabling detection of point mutations in human genomic DNA. Using a single primer, RCA generates hundreds of tandemly linked copies of a covalently closed circle in a few minutes. If matrix ...