Hosted on MSN1mon
First transgenic primate model created for hepatitis B research
Right now, nonhuman primate models are only attainable following temporary changes, like adding the HBV entry receptor, a human protein called NTCP, to liver cells with the help of viral vectors.
Investing29d
Assembly Biosciences initiates phase 1a trial for HDV treatment candidate
It will also measure serum bile acid levels as a biomarker for the drug's engagement with the sodium taurocholate cotransporting polypeptide (NTCP), which HDV uses to infect liver cells.