In this phase IA trial, 15 patients with classic and/or occult CNV were treated with a single intravitreal injection of Macugen TM. At 3 months, 80% of eyes showed stable or improved vision.
Fluorescein angiography enabled the identification of two major CNV patterns, known as 'classic' and 'occult' 55. Classic CNV is a discrete and well-demarcated area of hyperfluorescence ...
The fact that differentiation between classic and occult CNV and the recognition of the lesion components was not established until later on in the course of macular photocoagulation trials may ...
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