PME-1 is a protein that modifies other proteins by removing methyl groups, but high levels of PME-1 are observed in some ...

The roles of PP1, PP2A and PP2Cγ and PP2Cδ in pre-mRNA maturation ... and intronic regions are removed by a macromolecular complex known as the spliceosome. Exons can also be targeted for ...

SpringWorks is working to add another candidate to its clinical pipeline, with a filing to study the PP2A activator SW-3431 in humans planned for this year.