Our immune system relies on antibodies, a type of protein, to fight off bacteria and viruses transporting substances such as ...

Recent advances in biotechnology have fuelled the development of bispecific antibodies. However, there still remains a number of development challenges for those working in bioprocessing or cell line ...

Many proteins group together in what are called protein complexes to carry out biological functions. The traditional method of generating antibodies by immunizing animals struggles to make ...

A new study from Karolinska Institutet shows how a small antibody fragment can block fertilization by targeting a key protein ...

A major advantage of CITE-seq and REAP-seq is that, with an appropriate antibody, they can detect a protein of interest even if the RNA that encodes it is in low abundance. “CITE-seq gives us ...

Mapping an antibody’s epitope, where it binds a target, can now be done in three dimensions, which optimizes the selection of application-specific antibodies.

those to the acetylcholine receptor (AChR antibodies), those to muscle-specific kinase (MuSK), and those to low‐density lipoprotein receptor-related protein (LRP4). "All three types of ...

Antibody–drug conjugates have emerged as ... from immune agonist payloads to protein degrader payloads and novel cytotoxic payloads. “I’m particularly enthusiastic about our TOPO1 ADC ...

This enzymatic method enables highly specific and complete 1:1 protein conjugations with small molecules, solid supports, and other proteins, offering broad applicability across diverse biochemical ...

For antibodies and other protein-based biotherapeutics, extensive preclinical tests need to be conducted on animals before they can be tested on humans. Currently, antibody candidates are analyzed ...

Advancements in antibody technologies and protein data are driving new possibilities in cancer research, enabling the identification of novel biomarkers and enhancing therapeutic strategies. In this ...