Once transcription is initiated, the DNA double helix unwinds and RNA polymerase reads the template strand, adding nucleotides to the 3′ end of the growing chain (Figure 2b). At a temperature of ...

The method is based on a naturally occurring process called epigenetic modification—chemical changes to the DNA that affect ...

This enabled more complex molecules to form more often and also last longer, pairing up with the template to create more ...

DNA is essentially a storage molecule. It contains all of the instructions a cell needs to sustain itself. These instructions are found within genes, which are sections of DNA made up of specific ...

and each strand serves as a template for the synthesis of a new complementary strand. This semiconservative replication ensures that each daughter cell receives an exact copy of the genetic ...

It tracks processively along double helical DNA, untwists it to read the base pair sequence of only one strand and ... bacterial RNA polymerase may remain on the DNA template and be pulled to ...

Adenine on the template strand will always pair with thymine on the newly synthesized ... Several antiviral and anticancer drugs target the incorporation of adenine into DNA or RNA. For example, some ...

Overview of RNA repair – There is an emerging appreciation of the existence of “RNA repair” pathways that rely on RNA ligases to maintain or manipulate RNA structure in response to purposeful RNA ...

Now, scientists at Northwestern Medicine and the Broad Institute of MIT and Harvard have discovered an RNA that acts like the ...

ESGCT session on in vivo gene editing in preclinical model delivers new data from both Prime Medicine and Tessera ...

Cy5-labeled Fas siRNA with the fluorophore coupled to the 3' end of the sense strand ... 15 µg of total RNA and the In-vitro Transcription Kit and mouse mAPO-3 multi-probe template set (BD ...