Objective—Recent data suggested that sex hormone–binding globulin (SHBG) levels decrease when fat accumulates in the liver and that circulating SHBG may be causally involved in the ...

Chubb and colleagues, therefore, examined the relative contributions of levels of total testosterone, free testosterone and SHBG to this increased risk of metabolic syndrome. They found that ...

Sex-hormone-binding globulin (SHBG) reduces the levels of bioavailable estradiol and testosterone in circulating blood, which further increases fracture risk. Lee and colleagues investigated the ...

As mentioned above, higher androgen levels in females can cause overproduction of oils, leading to acne. High insulin can also lower sex hormone-binding globulin (SHBG), a protein that helps ...