When SHBG levels are low, more testosterone remains ... Hashimoto's disease is the most common cause of hypothyroidism in the United States, though there are other causes, too.

Two recently published studies using the Mendelian randomization approach provided strong evidence that circulating SHBG is directly involved in the pathogenesis of type 2 diabetes, both in men ...

Chubb and colleagues, therefore, examined the relative contributions of levels of total testosterone, free testosterone and SHBG to this increased risk of metabolic syndrome. They found that ...

Objective—Recent data suggested that sex hormone–binding globulin (SHBG) levels decrease when fat accumulates in the liver and that circulating SHBG may be causally involved in the ...