To enhance the potential of LCM and to overcome some of the limitations of other methods, we have developed a rapid, simple procedure for enrichment of normal and tumor cells called epithelial ...

Even simple animals like sponges have these proteins ... As an example, consider the epithelial cells that line the inner and outer surfaces of the human body — including the skin, intestines ...

Many events that shape the developing animal embryos involve rearrangements of simple epithelial sheets into more complex three ... activities are translated into coordinated changes in cell behavior: ...

The findings offer a promising drug target to prevent progression to colon cancer by targeting abnormal cells early on.

The gastric and duodenal mucosa possess defence mechanisms against digestive acids and pepsin, including mucus secretion, bicarbonate production, normal blood flow, and rapid renewal of damaged ...

Researchers have elucidated the role of the p53 gene in ulcerative colitis. The study suggests a potential new drug target to stop disease progression to cancer.

Other studies have shown that AM can serve as a culture substrate to expand epithelial progenitor cells for use in ocular surface reconstruction. Conclusion: AMT is an established technique in the ...

Results provide a mechanistic explanation of why early loss of p53 signaling is frequently observed in UC-associated ...

"The pluripotent stem cells—whether derived from blood or skin cells, carry the genetic traits of the patient, but have no way to know the inflamed environment inside the patient's gut," said Ghosh.

Ulcerative colitis is an inflammatory bowel disease that afflicts an estimated five million people worldwide and that is ...

Dietary protein absorption in neonatal mammals and fishes relies on the function of a specialized and conserved population of highly absorptive lysosome rich enterocytes (LREs). The gut microbiome has ...

A key role for p53: Ulcerative colitis affects the large intestine, specifically areas called "crypts," tube-like glands within the epithelial tissue that lines the intestine. Crypts contain stem ...