Cells have a natural editing system that allows them to rearrange genetic instructions to create different proteins from the ...

Alternative splicing (AS) of pre-mRNA plays a crucial role in tissue-specific gene regulation, with disease implications due to splicing defects. Predicting and manipulating AS can therefore uncover ...

The discovery could pave the way for a groundbreaking RNA-based multi-cancer treatment. Alternative RNA splicing functions ...

Plants survive cold by adjusting at cellular level. Scientists discovered that the PORCUPINE protein helps plants adapt to ...

Overview of RNA repair – There is an emerging appreciation of the existence of “RNA repair” pathways that rely on RNA ligases to maintain or manipulate RNA structure in response to purposeful RNA ...

Alternative RNA splicing is like a movie editor cutting and rearranging ... Interestingly, when researchers completely ...

Breakthrough discovery in cancer research! Scientists uncover a simple genetic strategy to combat aggressive cancers. Learn ...

A research team has uncovered new insights into the molecular mechanisms of ADAR1, a protein that regulates ribonucleic acid (RNA) induced immune responses. Their findings could open new pathways for ...

RBP splicing factors are sequence-specific, binding to their cognate sequence motifs like a lock and key. “Because the binding pocket of the RBP matches the sequence motif, the RBP binds to the ...

a leading developer of PPR genome-editing tools. Noncoding RNAs have been linked to the majority of diseases caused by dysregulation of gene activity and RNA splicing defects are thought to play a ...

The results of this work reveal how an alternative splicing mechanism regulates an essential factor for neuronal identity.