Rhodopsin is essential for photoreceptor survival. In the 8 December Science Chang and Ready report that rhodopsin's essential function is to organize actin and thus direct the photoreceptor's ...

[54] Recently, erlotinib has been found to induce activation of STAT3-Bcl2/Bcl-XL survival signaling, which has emerged as a new mechanism of resistance to TKIs. [66,67] Lung tumor cells ...

While the median overall survival time was not yet reached for the combo, investigators expect that the J&J regimen could offer at least an extra year of life versus Tagrisso, on which patients ...