VHL disease, a rare genetic disorder characterized by blood vessel tumors, frequently leads to RCC, a common form of kidney cancer. An estimated 10,000–15,000 Europeans suffer from VHL disease.

Kidney cancer incidences are rising among people under 50, linked to factors like obesity, hypertension, and smoking. This ...

Where? Does anything make your symptoms better or worse? Has anyone in your family had von Hippel-Lindau disease? What about kidney cancer? If the results show that you have renal cell carcinoma ...

A groundbreaking clinical trial shows how a personalized cancer vaccine primes the immune system to target kidney cancer ... in key RCC driver genes such as VHL, PBRM1, BAP1, KDM5C, and PIK3CA.

A clinical trial demonstrates that personalised cancer vaccines effectively target mutations in high-risk kidney cancer, ...

For example, let's say a patient has kidney cancer and they have specific gene mutations, such as von Hippel Lindell (VHL) germline mutations. If they do, I would consider them for evaluation by a ...

The treatment of adult patients with von Hippel-Lindau (VHL) disease who require therapy for associated, localized renal cell carcinoma (RCC), central nervous system (CNS) hemangioblastomas ...

The Dere lab specializes in kidney cancer and VHL (von Hippel Lindau) disease focused on understand fundamental aspects of how non-chromatin functions of chromatin modifiers contribute to oncogenesis.

The cohort had a median age of 65 years (IQR 53–68), with 74% male and 82% Caucasian. Of the total 808 gene panel, 15 genes were mutated by >5% in the entire cohort, with PBRM1, SETD2, KDM5C, TP53, ...

SESAUA annual meeting featured a kidney cancer session and a presentation by Dr. Robert Smith discussing how age and tumor ...