reverse transcription to form the linear viral DNA, and integration of that DNA into a chromosome of the host. The unintegrated DNA can also follow non-productive pathways, in which it is ...

The findings overturn the long-held idea that most types of RNA viruses are incapable of DNA integration and raise another safety concern in the use of RNA-based gene therapy. "It's a very interesting ...

While they've played a role in human evolution, they can also cause problems like cancer, brain disorders, and even aging.

The virus may offer insights into natural DNA integration processes useful for gene editing applications. Researchers identified the largest latent virus ever found in green algae. The virus ...

"It's a wonderful opportunity to learn how viral enzymes initiate DNA integration because they can be co-opted for biotechnological purposes." According to Aylward, Chlamydomonas reinhardtii is ...

The genome incorporation mechanism for LINE-1, the only autonomously active retrotransposon in humans, leverages the cell ...

Immunizing the host with a piece of viral DNA rather than an antigenic protein fragment of the virus, helps to stimulate the generation of cell-mediated immunity (Fig. 2). DNA vaccines contain the ...

Remnants of ancient viral pandemics in the form of viral DNA sequences embedded in our genomes are still active in healthy people, according to new research my colleagues and I recently published.

The Viral Vector & Plasmid DNA Manufacturing Market Size accounted for USD 5.4 Billion in 2023 and is estimated to achieve a market size of USD 24.6 Billion by 2032 growing at a CAGR of 18.5% from ...

Use the tweezers to pull out a segment of DNA from the hepatitis B virus. A subunit vaccine makes use of just a small portion of a pathogen. For a virus, the vaccine can contain just a piece of ...

More information: Kazuhisa Uchida et al, Encapsulation of a Single-Stranded Form of DNA Impurities into the Capsid of a Recombinant Adeno-Associated Virus, Human Gene Therapy (2025). DOI: 10.1089 ...

"It's a wonderful opportunity to learn how viral enzymes initiate DNA integration because they can be co-opted for biotechnological purposes." According to Aylward, Chlamydomonas reinhardtii is ...