In experiments in which the effects of phenylbutazone were studied with a single large dose of warfarin, 1.5 mg. per kilogram of body weight, the phenylbutazone was given in a dose of 200 mg.

The tool was developed using anonymized data from more than 1,000 heart surgery patients who were administered warfarin at St. Michael's Hospital between April 2011—November 2019. Data included ...

b These values are mean population values based on data from dabigatran doses ranging from 10 to 400 mg given as single and multiple doses. Adjusted-dosage warfarin 2.1 a p < 0.0001 for ...