After testing the targeting capabilities of several different DNA binding domains, the team settled on a zinc finger protein—a little curlicue-shaped protein that performed the best in terms of ...

C2H2 zinc finger proteins are the largest group of DNA-binding factors for transcription—the process of copying genetic information from DNA to messenger RNA (mRNA). As there are more than 700 ...

The monocytic leukemia zinc-finger protein (MOZ) gene is rearranged in ... Moreover, like MORF, MOZ possesses a weak transcriptional repression domain at its N-terminal part and a strong ...

The structures of a number of copper trafficking and sensing protein domains from different cellular ... literature (for example, in zinc finger proteins and iron-sulfur proteins).

In the past, this involved the adaptation of entire proteins or parts of proteins ... acid chain in the DNA-binding domain. This forms loops as a result (‘zinc fingers’) which can bind to DNA. Each ...