The off-label use of JAK inhibitors to treat JDM is common in pediatric rheumatology, with barriers to use including limited clinical trial data and insurance approval.

The study suggests that disturbances in the JAK-STAT signalling pathway ... to understanding why some drugs can have dangerous side effects like blood clots. And going forward, our method could ...

Delve into the kinase inhibitors' diverse landscape, from cancer breakthroughs to autoimmune disease innovations.

The study suggests that disturbances in the JAK-STAT signaling pathway ... identify and shed light on possible mechanisms of drug side effects," says one of the study's senior authors, associate ...

AbbVie has picked up another indication for its JAK inhibitor Rinvoq in the EU, becoming the first approved oral therapy for ...

Adverse events from disease-modifying antirheumatic drugs for the treatment of rheumatoid arthritis decline by as much as 25% after the drugs are established on the market, according to data published ...

Eli Lilly’s JAK inhibitor Olumiant has become the first ... “Dupilumab does not always work, and some people stop taking it because of side effects,” according to NICE’s technical ...

A prospective registry study found a greater risk for infections associated with JAK inhibitors in adolescents and adults with moderate to severe atopic dermatitis compared with biologics.

A study could be a step towards safer medications without serious side effects ... we see an increased risk of blood clots when using JAK inhibitors," explains Stine Rabech Haysen, former medical ...