B-cell acute lymphoblastic leukemia (B-ALL) is a life-threatening and highly aggressive form of blood cancer. It is the most ...

Oncologists are increasingly favoring CAR T-cell therapy’s early-line use in relapsed/refractory multiple myeloma despite ...

Researchers have harnessed synthetic biology to engineer chimeric antigen receptor (CAR) T cells that precisely target and destroy cancer. However, these powerful cells can also attack healthy tissues ...

The binding affinity of the Fc fragment towards ... evoke antibody-dependent cell-mediated cytotoxicity (ADCC). Thus, candidates should be tested against a panel of receptors at the time of ...

Rich, Noah T. Ditto, Larry Yu, Michael Friedman, Glory Gao, Spencer Chiang and Jane Liu from ACROBiosystems.. Fc-gamma receptors (FcγRs) are a group of cell surface proteins found on a range of ...

For the 80 million people worldwide with celiac disease, the only treatment available is to cut grains like pasta and bread out of their lives. | For the 80 million people worldwide who have celiac ...

Additional Phase 2 data for vilastobart,a tumor-activated, Fc-enhanced anti-CTLA-4, in combination with atezolizumab in patients with MSS CRC ...

CF patients, chronic pulmonary disease patients and hypogammaglobulinemics had accelerated Fc receptor mediated clearance rates (T 1/2 =19.6 min ... reticuloendothelial cell function and not ...

and the semidirect pathway, in which recipient T cells can be activated by acquired donor MHC molecules displayed on recipient APCs. APC: Antigen-presenting cell; TCR: T-cell receptor.

Receptors on B and T cells hint at what the immune system is targeting. An AI approach called Mal-ID developed increases diagnostic accuracy, particularly for autoimmune diseases. Your immune ...

Siltuximab effectively treated patients who experienced common adverse events after chimeric antigen receptor T-cell therapy, ...

It develops from the abnormal multiplication of T cells, or T-lymphocytes, a type of white blood cell essential for immune system function. The specific treatment course and prognosis for T-cell ...