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A-431 - CRL-1555 - ATCC
A-431 is a cell line exhibiting epithelial morphology that was isolated from the epidermis of an 85-year-old female patient with epidermoid carcinoma. This cell line is one of a series of cell lines established from solid tumors by D.J. Giard, et al. and can be used in cancer, toxicology, and immuno-oncology research.
A431 Cell Line - In-Depth Analysis of Epidermoid Carcinoma
A431 cells overexpress epidermal growth factor receptor (EGFR). They serve as a positive control for studying EGFR signalling and its implications in cancer. They are also used to evaluate new cancer therapies.
Cellosaurus cell line A-431 (CVCL_0037)
Culture of A-431 human epidermoid carcinoma cells in serum-free medium: effect of culture conditions on the binding of [125I]-epidermal growth factor. Different responses to EGF in two human carcinoma cell lines, A431 and UCVA-1, possessing high numbers of EGF receptors.
Human Skin Epidermoid Carcinoma Epithelial Cells (A-431)
The A-431 cell line, which was derived from an epidermoid carcinoma excised from the skin tissue of an 85-year-old female, is one of a succession of cell lines established from solid tumors by a research team led by D. J. Giard.
A431 Xenograft Model
A431 is a human epidermoid carcinoma cell line that was originally derived from a skin biopsy of a patient with vulvar squamous cell carcinoma. It is commonly used as a model for studying the biology of epithelial cancers, particularly those of the skin and mucous membranes.
A431 Cells - cytion.com
The A431 cell line, derived from a solid epidermoid carcinoma tumor in an 85-year-old female patient, is a human tumor cell line with an epithelial morphology, typically growing in clusters.
Growth characteristics of A431 human epidermoid carcinoma
Epidermal growth factor inhibits growth of A431 human epidermoid carcinoma in serum-free cell culture.
Metformin inhibits the proliferation of A431 cells by modulating …
Metformin treatment caused morphological change in A431 cells and inhibited their proliferation in a significant time- and dose-dependent manner. RT-PCR results showed that the mRNA expression of PI3K was inhibited by metformin in a time- and dose-dependent manner (P<0.05).
Comprehensive analysis of the genome transcriptome and …
We here present a comparative genome, transcriptome and functional network analysis of three human cancer cell lines (A431, U251MG and U2OS), and investigate their relation to protein expression. Gene copy numbers significantly influenced ...
Overexpression of CDC42SE1 in A431 Cells Reduced Cell …
We found that the expression of CDC42SE1 was reduced in human skin cancer samples relative to matched perilesional control. Exogenous expression of CDC42SE1 but not CDC42SE1 H38A (mutation within CRIB domain) in A431 cells (A431 SE1, …
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