Each ameloblast is a columnar cell approximately 4 micrometers in diameter, 40 micrometers in length and is hexagonal in cross section. The secretory end of the ameloblast ends in a six-sided pyramid-like projection known as the Tomes' process.

The ameloblast membrane resides at the interface between matrix and cell. Enamel formation is controlled by ameloblasts that produce enamel in stages to build the enamel layer (secretory stage) and to reach final mineralization (maturation stage).

The ameloblast controls the conformation and vector of movement of the secretory Tomes’ processes, which in turn dictates the orientations of the protein matrix.

The presumptive ameloblast begins its life cycle as a proliferative cell, low columnar in shape, separated from adjacent mesenchyme by a basement membrane. Once stimulated, the differentiating ameloblast ceases proliferation and begins to grow in height.

Sep 23, 2020 · The data show progressive modulation of transcription factor expression during different stages of ameloblast development (Fig. 4d–f), connecting known spatial and morphological transitions ...

Each Ameloblast is approximately 4 micrometers in diameter, 40 micrometers in length and has a hexagonal cross section. The secretory end of the ameloblast ends in a six sided pyramid like projection known as the Tomes' process.

Sep 21, 2012 · In this review, we describe how amelogenesis is highly integrated with ameloblast cell activities and how the shape, orientation and organization of enamel mineral ribbons are established by a ...

ameloblast A columnar epithelial cell that secretes tooth enamel, which has tapering apical surfaces and Tomes processes and which is embedded in the enamel matrix of the tooth.

Collectively, our findings integrate MEMO1 into an emerging network of molecules important for ameloblast development and provide a system to further interrogate the relationship of cytoskeletal and amelogenesis-related defects.

Aug 12, 2015 · By combining comparative analysis and coexpression networks, this study provides novel biomarkers and research targets for ameloblast differentiation and the potential for their application in enamel regeneration.