An axo-axonic synapse is a type of synapse, formed by one neuron projecting its axon terminals onto another neuron's axon. [1]Axo-axonic synapses have been found and described more recently than the other more familiar types of synapses, such as axo-dendritic synapses and axo-somatic synapses.

The chemical synapse is the principal form of contact between neurons of the central nervous system. These synapses are typically configured as presynaptic axon terminations onto postsynaptic dendrites or somata, giving rise to axo-dendritic and axo-somatic synapses, respectively. Beyond these commo …

Aug 2, 2024 · The axon initial segment (AIS) is a highly specialized cellular compartment localized at the proximal axon of the neuron. It serves as a gatekeeper by filtering the somato-dendritic proteins to maintain the neuronal polarity (1–4).AIS contributes to the initiation of action potential (AP) as it provides docking sites for high density of voltage-gated sodium channels, which …

3] axoaxonic — axon terminal branch synapses on another axon terminal branch (for presynaptic inhibition) or beside the initial segment of an axon; 4] dendrodendritic — dendrite synapsing on another dendrite (very localized effect). Synaptic ultrastructure: • The presynaptic enlargement (bouton, varicosity, or end plate) contains synaptic ...

Nov 13, 2024 · Axoaxonic: an interaction between the axon terminal of one neuron and the axon of another neuron. Dendrodendritic; an interaction between the dendrites of two neurons. Dendrosomatic; an interaction between the dendrites of one neuron and the the cell body (soma) of another neuron.

Ashrafi S, Betley JN, Comer JD, Brenner-Morton S, Bar V, Shimoda Y, Watanabe K, Peles E, Jessell TM, Kaltschmidt JA: Neuronal Ig/Caspr recognition promotes the formation of axoaxonic synapses in mouse spinal cord.

Neurons integrate synaptic inputs at the axon initial segment (AIS), where the action potential is initiated. Recent findings have shown this structure to be highly plastic. Here, we focus on the axo-axonic synapses formed onto the AIS and show that ...

axoaxonic synapse one between the axon of one neuron and the axon of another neuron.

Imbalance between excitation and inhibition in the cerebral cortex is one of the main theories in neuropsychiatric disorder pathophysiology. Cortical inhibition is finely regulated by a variety of highly specialized GABAergic interneuron types, ...

variants or axoaxonic also axo-axonal-ˈak-sən-ᵊl, -ak-ˈsän-, -ˈsōn- or axoaxonal: relating to or being a nerve synapse between an axon of one neuron and an axon of another … axo-axonic synaptic actions can increase the amount of transmitter released by the postsynaptic cell ...