Endosulfan is an organochlorine insecticide and acaricide, which acts by blocking the GABA-gated chloride channel of the insect (IRAC group 2A). [2] It became highly controversial [3] due to its acute toxicity, potential for bioaccumulation, and role as an endocrine disruptor.

Each peer-reviewed profile identifies and reviews the key literature that describes a hazardous substance's toxicologic properties. Other pertinent literature is also presented, but is described in less detail than the key studies. The complete list of topics covered (chapter titles) is shown at the left and in more detail further down this page.

Endosulfan is a man-made insecticide. It is used for control of a number of insects on food crops such as grains, tea, fruits, and vegetables and on nonfood crops such as tobacco and cotton. It is also used as a wood preservative.

Endosulfan is a restricted-use pesticide. It is particularly effective against aphids, fruit worms, beetles, leafhoppers, moth larvae, and white flies on a wide variety of crops. Endosulfan is sold as a mixture of two different forms of the same chemical (referred to as α- and β-endosulfan).

May 18, 2022 · These fact sheets summarize the information on occurrence and health effects of the chemicals covered, presenting guideline values where these have been derived and the basis for their derivation, or where guideline values have not been derived, the rationale for not establishing such values.

Important physical and chemical properties of endosulfan, α-endosulfan, β-endosulfan, and endosulfan sulfate are listed in Tables 4-5, 4-6, 4-7, and 4-8, respectively. It should be noted that β-endosulfan is slowly converted to α-endosulfan (Hapeman et al. 1997; Rice et al. 1997).

Endosulfan is a restricted-use pesticide. It is particularly effective against aphids, fruit worms, beetles, leafhoppers, moth larvae, and white flies on a wide variety of crops. Endosulfan is sold as a mixture of two different forms of the same chemical (referred to as α- and β-endosulfan).

Benzoepin, Endosulphan, 6,7,8,9,10-Hexachloro-1,5,5a,6,9,9a-hexachloro-6,9-methano-2,4,3-benzo-dioxathiepin-3-oxide, Thiodan®. Brown crystals with a slight, sulfur dioxide odor. [insecticide] [Note: Technical product is a tan, waxy, isomer mixture.] Noncombustible Solid, but may be dissolved in flammable liquids.

Endosulfan is an organochlorine insecticide and acaricide that is being phased out globally due to its acute toxicity. In 2011, the Stockholm Convention initiated a global ban on the manufacture and use of this chemical because of its threats to the environment and human health.

In humans, endosulfan appears to accumulate in the liver, kidney, and brain, at least in the short term. In animals, endosulfan is transformed predominantly to polar and nonpolar metabolites by liver microsomal enzymes. Endosulfan and metabolites have been detected in the urine of humans after ingestion of the chemical.