Esketamine, sold under the brand names Spravato (for depression) and Ketanest (for anesthesia) among others, [10][12] is the S (+) enantiomer of ketamine. [5][13] It is a dissociative hallucinogen drug used as a general anesthetic and as an antidepressant for treatment of depression.

There’s good news for people with severe treatment-resistant depression: Esketamine is a groundbreaking therapy that can provide relief from major depression within hours.

Apr 22, 2024 · Easy-to-read patient leaflet for Esketamine. Includes indications, proper use, special instructions, precautions, and possible side effects.

Apr 1, 2025 · Esketamine nasal spray is used together with an antidepressant taken by mouth, to treat patients with depression who have previously received at least 2 antidepressant treatments that did not work well (treatment-resistant depression).

Esketamine is the only pharmacological agent with glutamatergic neuromodulatory properties approved by the US Food and Drug Administration (FDA) and European Medicines Agency (EMA) in 2019 to enhance the effects of serotonin selective or …

Learn about SPRAVATO® (esketamine) nasal spray, a prescription medicine for two indications. See full Prescribing & Safety Info, including BOXED WARNINGS.

Esketamine is an intranasal antidepressant medication that works in the brain. It is FDA approved for the treatment of major depressive disorder (MDD) with suicidal thoughts and behavior as well as treatment-resistant depression (TRD) in conjunction with an oral antidepressant.

Nov 4, 2024 · Esketamine is a nasal spray that is used together with an oral (taken by mouth) antidepressant to treat adults with depression that is resistant to other treatments. Esketamine is also used with an antidepressant taken by mouth to treat symptoms of depression in adults with major depressive disorder who have suicidal thoughts or actions.

Mar 9, 2020 · Below, Dr. Murrough breaks down the top five things to know about esketamine based on his experience over the past decade. 1. What it is. Esketamine is a potent variant of the drug ketamine, which has been used for 50 years in …

Esketamine nasal spray is used alone or in combination with another antidepressant, taken by mouth, to manage treatment-resistant depression (TRD; depression that does not improve with treatment) in adults.