Mar 22, 2023 · Your immune system is the network of cells and tissues in your body that work together to defend you from viruses, bacteria, and infection. It tries to identify and destroy the invaders that might hurt you. In autoimmune diseases, proteins known as autoantibodies target the body’s own healthy tissues by mistake, signaling the body to attack them.

Immune system changes. Abnormal immune or inflammatory activity in your body triggers cell changes that cause the production of too much collagen. In some cases, an immune reaction to developing cancer cells may trigger scleroderma. Hormones. Women develop most types of scleroderma more often than men.

Mar 22, 2023 · In autoimmune diseases, proteins known as autoantibodies target the body’s own healthy tissues by mistake, signaling the body to attack them.

Mar 22, 2023 · In autoimmune diseases, proteins known as autoantibodies target the body’s own healthy tissues by mistake, signaling the body to attack them.

Sjögren’s disease, also known as Sjögren’s and Sjögren’s syndrome, is a chronic (long-lasting) autoimmune disorder that happens when the immune system attacks the glands that make moisture in the eyes, mouth, and other parts of the body. The main symptoms are dry eyes and mouth, but other parts of the body may be affected as well, with ...

Jul 22, 2019 · It is a disease where the immune system attacks healthy cells in the top layer of skin, resulting in blisters. Polymyalgia Rheumatica and Giant Cell Arteritis Polymyalgia rheumatica and giant cell arteritis are closely linked inflammatory conditions.

Jun 6, 2022 · Sometimes, your immune system makes mistakes. If it sees your body’s healthy cells as a threat, it may attack them. This can cause an autoimmune disorder.

Normally, the immune system works throughout your body to fight off and defend your body from viruses, bacteria, and infection. In people with autoimmune diseases, the immune cells attack the body’s own healthy tissues by mistake. People with vitiligo may be more likely to develop other autoimmune disorders as well.

The cause of lupus is unknown, and researchers are still trying to learn what may trigger or lead to the disease. Doctors know that it is a complex autoimmune disease in which the body’s immune system attacks the person’s tissues and organs. Studies show that certain factors may trigger your immune system, causing the disease.

Mar 10, 2025 · The Accelerating Medicines Partnership® Autoimmune and Immune-Mediated Diseases (AMP® AIM) program launched in 2021 with the goal of deepening our understanding of the cellular and molecular interactions that lead to inflammation and autoimmune diseases.