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  1. GeneCards
    https://www.genecards.org › cgi-bin › carddisp.pl

    LIN28A Gene - GeneCards | LN28A Protein | LN28A Antibody

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  2. GeneCards
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    LIN28B Gene - GeneCards | LN28B Protein | LN28B …

    Oct 2, 2024 · LIN28B is a protein coding gene that regulates microRNA biogenesis and is involved in cellular transformation and pluripotency. It is highly expressed in testis, fetal liver, placenta, and some cancers. Learn more about …

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  3. Wikipedia
    https://en.wikipedia.org › wiki

    LIN28 - Wikipedia

  4. GeneCards
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    lin28 related genes - GeneCards Search Results

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    Lin28b Cell Signal
    Lin28b Gene
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  5. PubMed
    https://pubmed.ncbi.nlm.nih.gov

    Lin28, a major translation reprogramming factor, gains access to …

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    Lin28b Gene
    Lin28b Cell Signal
    Lin28a Regeneration
    Publish Year:2021
  6. biologists.com
    https://journals.biologists.com › dev › arti…

    LIN28: roles and regulation in development and beyond

    Jul 15, 2015 · LIN28 is an RNA-binding protein that is best known for its roles in promoting pluripotency via regulation of the microRNA let-7. However, recent studies have uncovered new roles for LIN28 and have revealed how it …

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    Publish Year:2015
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  7. People also ask
    What is Lin28a gene?
    LIN28A (Lin-28 Homolog A) is a Protein Coding gene. Diseases associated with LIN28A include Medulloepithelioma and Embryonal Tumor With Multilayered Rosettes, C19mc-Altered. Among its related pathways are Nervous system development and Burn wound healing.

    LIN28A Gene - GeneCards | LN28A Protein | LN28A Antibody

    genecards.org
    How does LIN28 bind to mRNA?
    The RNA-binding protein Lin28 (Lin28a) is an important pluripotency factor that reprograms translation and promotes cancer progression. Although Lin28 blocks let-7 microRNA maturation, Lin28 also binds to a large set of cytoplasmic mRNAs directly. However, how Lin28 regulates the processing of many …

    Lin28, a major translation reprogramming factor, gains access ... - PubMed

    pubmed.ncbi.nlm.nih.gov
    What is LIN28 RNA binding protein?
    3 Institute of Protein Research, Russian Academy of Sciences, Pushchino, 142290, Russian Federation. The RNA-binding protein Lin28 (Lin28a) is an important pluripotency factor that reprograms translation and promotes cancer progression. Although Lin28 blocks let-7 microRNA maturation, Lin28 also binds to a large set of cytoplasmic mRNAs directly.

    Lin28, a major translation reprogramming factor, gains access ... - PubMed

    pubmed.ncbi.nlm.nih.gov
    What is LIN28B gene ontology?
    Gene Ontology (GO) annotations related to this gene include nucleic acid binding and mRNA binding. An important paralog of this gene is LIN28B. RNA-binding protein that inhibits processing of pre-let-7 miRNAs and regulates translation of mRNAs that control developmental timing, pluripotency and metabolism (PubMed: 21247876).

    LIN28A Gene - GeneCards | LN28A Protein | LN28A Antibody

    genecards.org
    What is LIN28 homolog A?
    Lin-28 homolog A is a protein that in humans is encoded by the LIN28 gene. LIN28 encodes an RNA -binding protein that binds to and enhances the translation of the IGF-2 (insulin-like growth factor 2) mRNA.

    LIN28 - Wikipedia

    en.wikipedia.org
    Does LIN28 enhance gene translation in human embryonic stem cells?
    Elife. 2019;8:e50163. Ito K, Suda T. Metabolic requirements for the maintenance of self-renewing stem cells. Nat Rev Mol Cell Biol. 2014;15:243–56. Peng S, Chen LL, Lei XX, Yang L, Lin H, Carmichael GG, et al. Genome-wide studies reveal that Lin28 enhances the translation of genes important for growth and survival of human embryonic stem cells.

    LIN28A enhances regenerative capacity of human somatic tissue stem

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  8. Nature
    https://www.nature.com › articles

    LIN28A enhances regenerative capacity of human somatic tissue …

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    Stem Cells
    Lin28a Regeneration
    Publish Year:2021
    Hsp60 Lin28b
  9. Cell Press
    https://www.cell.com › cell-stem-cell › fulltext

    LIN28 Regulates Stem Cell Metabolism and Conversion …

    Proteomic and metabolomic analysis highlighted roles for LIN28 in maintaining the low mitochondrial function associated with primed pluripotency and in regulating one-carbon metabolism, nucleotide metabolism, and histone …

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    Publish Year:2016
    Stem cell
  10. National Center for Biotechnology Information
    https://www.ncbi.nlm.nih.gov › gene

    LIN28A lin-28 homolog A [ Homo sapiens (human) ] - National …

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    Stem Cells
    Lin28a Regeneration
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    Homo sapiens
  11. OMIM
    https://www.omim.org › entry

    Entry - *611043 - LIN28 HOMOLOG A; LIN28A - OMIM

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    Stem Cells
    LIN28A