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Nucleic acid test - Wikipedia
A nucleic acid test (NAT) is a technique used to detect a particular nucleic acid sequence and thus usually to detect and identify a particular species or subspecies of organism, often a virus or bacterium that acts as a pathogen in blood, tissue, urine, etc. NATs differ from other tests in that they detect genetic materials (RNA or DNA) rather ...
Nucleic acid detection with CRISPR-Cas13a/C2c2 | Science - AAAS
Apr 13, 2017 · Methods are needed that can easily detect nucleic acids that signal the presence of pathogens, even at very low levels. Gootenberg et al. combined the allele-specific sensing ability of CRISPR-Cas13a with recombinase polymerase amplification methods to detect specific RNA and DNA sequences.
Nucleic Acid Amplification Tests (NAATs) | CDC - Centers for …
May 12, 2023 · A Nucleic Acid Amplification Test, or NAAT, is a type of viral diagnostic test for SARS-CoV-2, the virus that causes COVID-19. NAATs detect genetic material (nucleic acids). NAATs for SARS-CoV-2 specifically identify the RNA (ribonucleic acid) sequences that comprise the genetic material of the virus.
Rapid and comprehensive detection of viral antibodies and nucleic acids …
Jan 15, 2025 · Nucleic acid testing and immunity protein (antibody) detection are widely used diagnostic tools in tracking population health during outbreaks of infectious diseases. Nucleic acid testing is highly sensitive and can detect a pathogen’s genetic material (RNA or DNA), even in the early stages of infection.
Nucleic Acid Based Tests - FDA
Sep 23, 2024 · These tests analyze variations in the sequence, structure, or expression of deoxyribonucleic acid (DNA) and ribonucleic acid (RNA) in order to diagnose disease or medical conditions, infection...
Recent advancements in nucleic acid detection with microfluidic …
Jan 1, 2023 · In this review, we first summarized the routine process of nucleic acid testing, including sample processing and nucleic acid detection. Then the typical microfluidic chip technologies and new research advances are summarized. We also discuss the main problems of nucleic acid detection and the future developing trend of the microfluidic chip. 1.
Nucleic Acid–Based Identification Methods for Infectious Disease
Nucleic acid–based (molecular) identification has become commonplace in clinical settings; the resulting rapid identification allows the patient to be placed on specific antimicrobial therapy and avoid prolonged management on empiric, potentially inappropriate medications.
SHERLOCK: nucleic acid detection with CRISPR nucleases
Sep 23, 2019 · Rapid detection of nucleic acids is integral to applications in clinical diagnostics and biotechnology. We have recently established a CRISPR-based diagnostic platform that combines nucleic...
Recent developments and trends of automatic nucleic acid detection ...
Nucleic acid detection mainly includes three steps: 1) nucleic acid extraction, 2) amplification system preparation, and 3) polymerase chain reaction (PCR) amplification. It is mainly completed in three or four independent closed areas of a molecular laboratory.
Detection of Nucleic Acids and Proteins - The Cell - NCBI Bookshelf
The key to detection of specific nucleic acid sequences is base pairing between complementary strands of RNA or DNA. At high temperatures (e.g., 90 to 100°C), the complementary strands of DNA separate (denature), yielding single-stranded molecules.
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