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Trichothecene - Wikipedia
Trichothecenes are mycotoxins produced by molds that frequently contaminate stores of grain products. This makes trichothecene contamination a significant public health problem, and many areas have strict limits on permitted trichothecene content.
Trichothecenes: From Simple to Complex Mycotoxins - PMC
Trichothecenes are a family of over 200 toxins with a common tricyclic 12,13-epoxytrichothec-9-ene (EPT) core structure (Figure 1) [5, 28]. They have been classified into four groups (Types A, B, C, and D) based on the substitution pattern of EPT (Figure 1) [29, 30].
Trichothecene Mycotoxins, Symptoms, T-2 - Moldpedia
Trichothecene is one of the most notorious mycotoxins because trichothecenes are extremely toxic and because they are so difficult to destroy. One reason why trichothecene is such a well known mycotoxin is because it is produced by (also called toxic black mold or just black mold).
Trichothecenes in Food and Feed, Relevance to Human and …
Trichothecenes are groups of chemically related toxins formed by some filamentous fungal species such as Fusarium, Myrothecium, and Stachybotrys.
Trichothecene Group - Lab Results explained | HealthMatters.io
Trichothecenes directly act with cellular organelles and structures causing inhibition of protein, RNA and DNA synthesis, disaggregation of polyribosomes and rough endoplasmic reticulum, inhibition of mitochondrial functions and cause cell death (apoptosis).
Trichothecenes - You Are The Healer
Trichothecenes are small molecules and can move passively across cell membranes. They are easily absorbed by the skin and the gastrointestinal system, allowing for immediate effect on tissues with rapid cell turnover.
Trichothecene - an overview | ScienceDirect Topics
Trichothecenes are a large family of chemically related mycotoxins produced by various species of Fusarium, which is the most economically important fungal strains. Trichothecenes have most often been associated with acute and chronic toxicoses in human and livestock.
Trichothecenes: from simple to complex mycotoxins - PubMed
A number of the molds that are plant pathogens produce trichothecene mycotoxins, which are known to cause serious human and animal toxicoses. This review covers the types of trichothecenes, their complexity, and proposed biosynthetic pathways of trichothecenes.
Trichothecene Toxicosis in Animals - MSD Veterinary Manual
The trichothecene mycotoxins are highly toxic at the subcellular, cellular, and organic system level. Trichothecenes inhibit protein synthesis by affecting ribosomes to interfere with protein synthesis and covalently bond to sulfhydryl groups.
T-2 Toxin—The Most Toxic Trichothecene Mycotoxin: Metabolism …
Nov 14, 2021 · Among trichothecenes, T-2 toxin is the most toxic fungal secondary metabolite produced by different Fusarium species. Moreover, T-2 is the most common cause of poisoning that results from the consumption of contaminated cereal-based food and feed reported among humans and animals.