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  1. Verywell Health
    https://www.verywellhealth.com/pvns-symptoms-causes-diagnosis-and-treatment-4682674

    Pigmented Villonodular Synovitis (PVNS) Joint Pain

    • This condition typically affects adults before age 50, and it can have a tendency to grow or recur in the same location after treatment. PVNS typically affects only one joint, but it can affect more than one joint in … See more

    What Causes Pigmented Villonodular Synovitis?

    PVNS is caused by overgrowth and thickening of the synovium. Synovium, which is also called synovial lining, is a thin capsule that encloses the joint and produces … See more

    Verywell Health
    How to Diagnose Pigmented Villonodular Synovitis

    This type of tumor can be evaluated based on your history and test results. If you have symptoms of PVNS, you may have one or more of the following evaluations: 1. Physical ex… See more

    Verywell Health
    How Do You Treat Pigmented Villonodular Synovitis?

    Once you have a diagnosis of PVNS, over-the-counter or prescription-strength anti-inflammatory medication may be helpful to reduce your swelling and discomfort. Because th… See more

    Verywell Health
    Summary

    PVNS has been described as a growth or a tumor in the lining of the joint. While it is accurately labeled as a tumor, it is not cancer and it is not typically life-threatening. However, P… See more

    Verywell Health
    What happens if a person develops a PVNS?
    The abnormal synovial lining caused by PVNS results in joint swelling, can sometimes interfere with movement, and may grow into and destroy nearby joint structures, including bone in severe cases. The reason that a person develops PVNS is not known.
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    Table of Contents
    What Causes Pigmented Villonodular Synovitis?
    How to Diagnose Pigmented Villonodular Synovitis
    How Do You Treat Pigmented Villonodular Synovitis?
    Summary
    What happens if a person develops a PVNS?
     
  1. PVNS is a progressive disease. Left untreated, PVNS will slowly get worse and can lead to bone damage, arthritis, and limited range of movement in the affected joint. PVNS isn't life-threatening and doesn’t spread beyond the affected joint. But it can affect your ability to move and your quality of life.

    Pigmented Villonodular Synovitis (PVNS) Causes, Symptoms, Tre…

    www.upmc.com/services/orthopaedics/conditions/pvns
    www.upmc.com/services/orthopaedics/conditions/pvns
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    What happens if PVNS is left untreated?
    PVNS is a progressive disease. Left untreated, PVNS will slowly get worse and can lead to bone damage, arthritis, and limited range of movement in the affected joint. PVNS isn't life-threatening and doesn’t spread beyond the affected joint. But it can affect your ability to move and your quality of life.

    Pigmented Villonodular Synovitis (PVNS) Causes, Symptoms, Treatment…

    upmc.com
    Is PVNS a progressive disease?
    However, PVNS is a progressive disease. It slowly worsens and can lead to bone damage and arthritis. PVNS usually affects the knee, although it can affect other joints as well. In most cases, surgery is needed to remove the damaged joint lining and the mass.

    Pigmented Villonodular Synovitis - OrthoInfo - AAOS

    orthoinfo.aaos.org
    What happens if a person develops a PVNS?
    The abnormal synovial lining caused by PVNS results in joint swelling, can sometimes interfere with movement, and may grow into and destroy nearby joint structures, including bone in severe cases. The reason that a person develops PVNS is not known.

    Pigmented Villonodular Synovitis (PVNS) Joint Pain - Verywell Health

    verywellhealth.com
    How do you know if you have PVNS?
    Signs of PVNS include: Hemarthrosis, or bleeding inside a joint, without any noticeable injury. The area around the joint may look bruised or discolored. Instability in the joint. Popping, locking, or catching when you move the joint. Stiffness and swelling in a joint, most often the knee. Symptoms that come and go and get worse as time goes by.

    Pigmented Villonodular Synovitis (PVNS) Causes, Symptoms, Treatment…

    upmc.com
    What are the different types of PVNS?
    There are two forms of PVNS—localized and diffuse. When the tumor involves the tendons that support the joint, or occurs in just one area of the joint, it is called localized PVNS. This type usually responds well to treatment. When the condition is more widespread and involves an entire joint, it is called diffuse PVNS.

    Pigmented Villonodular Synovitis - OrthoInfo - AAOS

    orthoinfo.aaos.org
    How common is PVNS?
    Estimates show that around four or five people out of every 10,000 will have this condition, which is commonly diagnosed between ages 30 and 50. Usually, PVNS is found in only one joint. In 80% of cases, this will be one of the knee joints.

    What Is (PVNS) Pigmented Villonodular Synovitis? - WebMD

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  3. OrthoInfo
    https://orthoinfo.aaos.org/en/diseases …

    Pigmented Villonodular Synovitis - OrthoInfo - AAOS

    Pigmented villonodular synovitis (PVNS) is a condition that causes the synovium to thicken and overgrow, forming a mass or tumor in the joint. It can affect any joint, but most often the knee, and may require surgery to …

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  4. DoveMed
    https://www.dovemed.com/health-topics/focused...

    Pigmented Villonodular Synovitis (PVNS): Understanding a Rare

  5. UPMC
    https://www.upmc.com/services/orthopaedics/conditions/pvns

    Pigmented Villonodular Synovitis (PVNS) Causes, Symptoms, …

  6. National Center for Biotechnology Information
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7467432

    Identification of Patient Needs and Preferences in Pigmented ...

  7. WebMD
    https://www.webmd.com/pain-management/knee-pain/...

    What Is (PVNS) Pigmented Villonodular Synovitis? - WebMD

  8. lww.com
    https://journals.lww.com/md-journal/Fullte…

    Long-term functional outcomes of diffuse pigmented.

    Mar 26, 2021 · Therefore, although classified as a benign disease, diffuse PVNS could cause severe disability at a relatively young age. Despite having a high recurrence rate and possible severe joint function decline, there is a lack of …

  9. Healthline
    https://www.healthline.com/health/tgct/…

    Pigmented Villonodular Synovitis (PVNS) Treatment

    Jun 16, 2022 · In pigmented villonodular synovitis, the synovium swells. It isn’t cancer but can cause complications. Here’s what you need to know about PVNS treatment.

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  10. National Center for Biotechnology Information
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2231588

    Diffuse pigmented villonodular synovitis of the foot and ankle …