- Cytochromes P450 (P450s or CYPs) are a superfamily of enzymes containing heme as a cofactor that mostly, but not exclusively, function as monooxygenases1. A distinct family of cytochromes is the cytochrome P450 family, so named for the characteristic Soret peak formed by absorbance of light at wavelengths near 450 nm when the heme iron is reduced (with sodium dithionite) and complexed to carbon monoxide2. These enzymes are primarily involved in steroidogenesis and detoxification2.Learn more:âś•This summary was generated using AI based on multiple online sources. To view the original source information, use the "Learn more" links.Cytochromes P450 (P450s or CYPs) are a superfamily of enzymes containing heme as a cofactor that mostly, but not exclusively, function as monooxygenases.en.wikipedia.org/wiki/Cytochrome_P450A distinct family of cytochromes is the cytochrome P450 family, so named for the characteristic Soret peak formed by absorbance of light at wavelengths near 450 nm when the heme iron is reduced (with sodium dithionite) and complexed to carbon monoxide. These enzymes are primarily involved in steroidogenesis and detoxification.en.wikipedia.org/wiki/Cytochrome
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See all on WikipediaCytochrome P450 (individual enzymes) - Wikipedia
Cytochrome P450 enzymes play roles in hormone synthesis and breakdown (including estrogen and testosterone synthesis and metabolism), cholesterol synthesis, and vitamin D metabolism. See more
Animals
Other animals often have more P450 genes than humans do. Reported numbers range from 35 genes in the sponge See moreHuman P450s are primarily membrane-associated proteins located either in the inner membrane of mitochondria or in the endoplasmic reticulum of … See more
• Degtyarenko K (2009-01-09). "Directory of P450-containing Systems". International Centre for Genetic Engineering and Biotechnology. Archived from the original on 2016-07-16. Retrieved 2009-02-10.
• Flockhart DA (2008-09-04). "Human Cytochrome P450 … See moreWikipedia text under CC-BY-SA license List of cytochrome P450 modulators - Wikipedia
This is a list of cytochrome P450 modulators, or inhibitors and inducers of cytochrome P450 enzymes.
Wikipedia · Text under CC-BY-SA license- Studies of Cytochrome P450 Wikipedia
Cytochrome - Wikipedia
A distinct family of cytochromes is the cytochrome P450 family, so named for the characteristic Soret peak formed by absorbance of light at wavelengths near 450 nm when the heme iron is …
Cytochrome P450 Structure, Function and Clinical Significance
Abstract. Background: The cytochrome P450 (CYP) enzymes are membrane-bound hemoproteins that play a pivotal role in the detoxification of xenobiotics, cellular metabolism and …
The Role of Cytochromes P450 in Infection - PMC
The main cytochrome P450 (CYP) enzymes and their role in host homeostasis. The most abundant CYP enzymes are CYP3A4 and CYP2D6 and they are expressed in the liver but …
Cytochrome P450 - Wikiwand
Cytochromes P450 (P450s or CYPs) are a superfamily of enzymes containing heme as a cofactor that mostly, but not exclusively, function as monooxygenases. [1] However, they are not …
Cytochrome P450 - SpringerLink
Sep 11, 2021 · The cytochrome P450 (CYP450, also abbreviated CYPs) is a large superfamily of heme-proteins (they contain the organic cofactor heme, a prosthetic group crucial for their …
Cytochrome P450 Structure and Function: An Evolutionary …
Jun 27, 2008 · The cytochromes P450 constitute a superfamily of haem-thiolate enzymes which are ubiquitous in nature. 1,2 Figure 1.1 shows the many fields in which P450s play important …
SuperCYP: a comprehensive database on Cytochrome P450 …
Nov 24, 2009 · Much of the information on the Cytochrome P450 enzymes (CYPs) is spread across literature and the internet. Aggregating knowledge about CYPs into one database …
57 varieties: the human cytochromes P450 - PubMed
This review covers the extent of enzyme functionality for the known human P450s, focusing primarily on their role in the Phase I metabolism of foreign compounds, which involves the …
