Deseronto is a town in the Canadian province of Ontario, in Hastings County, located at the mouth of the Napanee River on the shore of the Bay of Quinte, on the northern side of Lake Ontario. It is located 5 km from Highway 401, is the eastern gateway to the Bay of Quinte tourist region, with the Skyway Bridge providing access to Prince Edward County. This is the most easterly municipality of Hastings County. It was a center of industry related to timber and mineral resources until the 1930s.